bap1 pb empower plan
in human lung models, Molecular determinants of host adaptation in fungal-plant pathogens: origins and evolution of virulence effectors by genomic, phylogenetic and association mapping studies. Nanoparticle-based immunization, a novel therapeutic strategy for amyotrophic lateral sclerosis, Investigating the role of OPN-CD44 in mechanosensitive tumour invasion using biomimetic models, RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis, Gluten Epitope Molecularly imprinted polymer Sensor, Dental anthropology at the Pleistocene-Holocene transition – insights on lifestyle and funerary behaviour from Neolithic Liguria (Italy), Matched Sampling Approaches for Statistical Inference in Large-Scale Clinical Neuroimaging Studies, Molecular profiling of Bladder Cancer to support personalized medicine, Assessment of Reserve: Translational Evaluation of Medical Images and Statistics-Prediction models for outcomes of brain health, Innovative training in methods for future data, A regional history of medicine in the modern Middle East, 1830-1960, The chemistry and physics of RNP granules: how they form, age and cause disease, At the host-bacteria interface: Modulation of the intestinal microbiota and its metabolic activity by Card9 signalling in health and Inflammatory Bowel Diseases. Mucosal Tolerance and Allergic Predisposition: Does it all start in the gut? Magnification of Asthma by human memory Group 2 Innate lymphoid Cells, Cortical markers of L-DOPA-induced dyskinesias, The role of CD63 in lysosomal degradation of insulin granules in pancreatic beta cells in T2D diabetes, Deciphering the Transcriptional Logic of TFEB activation in cell identity and cancer, Role of miR-129-5p and Rbfox1 crosstalk in neural network homeostasis, The Role of OSTα/β as a Bile Acid and Drug Transporter in Obesity-Associated Chronic Liver Disease, Nonalcoholic Fatty Liver Disease, Unravelling pathogen evolution breaking down crop resistance in agricultural ecosystems, Understanding selective neuronal vulnerability in Alzheimer’s disease, Skin Keratinocyte Stem CEll proliferatioN in field CancErisation, Tumor-Targeting Nanoengineered Bioorthogonal Technologies to Fight Metastatic Cancers, Structural Openings to Understand and Prevent Tick Borne Encephalitis, Multi-omics molecular treatment targets for Prostate Cancer. Validating C. elegans healthspan model for better understanding factors causing health and disease, to develop evidence based prevention, diagnostic, therapeutic and other strategies. Bioinformatics platform for profiling of health: allowing early and accurate detection of multiple diseases simultaneously, Toilet IoT sensor for medical monitoring and wellness tool, Development of an innovative Airway-on-Chip microbiome cell culture model to investigate host-microbiome interactions at the airway epithelial surface, How dopamine affects social and motor ability - from the human brain to the honey bee, What is Tuberculosis? ALTERNATIVE SPLICING NETWORKS IN PANCREATIC BETA CELLS, Roles of spastic paraplegia proteins in organisation of axonal endoplasmic reticulum, Ex vivo Re-vascularization in Porcine Liver Bioengineering - A Critical First Step Towards Effective Transplantation of Bioengineered Livers, Rewiring Brain Units - bridging the gap of neuronal communication by means of intelligent hybrid systems, Micro-RNAs of neutrophils in renal ANCA-associated vasculitis, Selective vulnerability of neuronal degeneration in Parkinson’s disease: the load of routine behaviour, Identification and characterization of new cytosolic ligands of Sortilin, Characterising the spatial organisation and regulation of the Wnt receptor complex in stem cells and cancer. This report presents a female patient with a primary pineal melanoma who underwent subtotal resection followed by adjuvant focal radiation to the residual tumor. Decoding impairments of gait and balance from local field potentials in patients with Parkinson's disease. A Non-Invasive GLUCOse MONitoring device for diabetics based on Stimulated Raman Spectroscopy in a quick, cheap and painless method. Background. Diabetes Approach by Multi-Organ-on-a-Chip, Quantitative analysis of variability and robustness in spatial pattern formation, The chemical understanding of biomolecular recognition in epigenetics, Gut microbiota-dependent tryptophan metabolism: role in disease pathogenesis and therapeutic target, Towards enduring mouse resources and services advancing research into human health and disease, Paediatric Clinical Research Infrastructure Network, Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer, Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine, RECAP preterm: Research on European Children and Adults born Preterm, Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial, Implementation of cost-optimized childhood vision and hearing screening programmes in middle-income countries in Europe, MetaMaterials antenna for ultra-high field MRI, Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals, 3-O-sulfated heparan sulfate translocation in altered membrane biology: A new strategy for early population screening and halting Alzheimer’s neurodegeneration, Host switching pathogens, infectious outbreaks and zoonosis; a Marie Sklodowska-Curie Training Network, Pathoecology of Vibrio cholerae to better understand cholera index cases in endemic areas, Novel treatment for peripheral arterial disease. The genetic basis for glial differentiation in the developing zebrafish retina. Discovering functional protein-RNA interactions through data integration and machine learning. From pills to bio-electronics: a wearable anti-inflammatory treatment for prevention of Peripheral Arterial Disease. Integral cell-biology platform for the development of the first effective treatment of radiodermatitis. Bacterial Amyloid Secretion: Structural Biology and Biotechnology. The spatial organization of declarative knowledge, Development of new chemical tools to combat ALS, Unravelling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis. Connectivity, plasticity and function of an olfactory memory circuit, A new innovative method for diabetes treatment, the artificial pancreas system, Super-resolution genomic mapping for the microbiome, Advanced Solutions for High Sensitivity Metabolism and Toxicity Assays, New MilliDrop Analyzer: miniaturized and faster clinical microbiology testing in only one drop, Developing Smart 3D Scaffolds based on Conductive Polymers and Carbon Nanotubes for Cardiac Tissue Engineering, Neuroimmune activation as a novel therapeutic approach for IBD, Development of a policy to stop the suffering caused by Nodding Syndrome and Onchocerciasis associated epilepsy, Assay for cancer diagnostics by quantification of 5hmC, PoC in-office device for identifying individuals at high risk of Osteoporosis and osteoporotic fracture, Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome, Scalable inference algorithms for Bayesian evolutionary epidemiology, Affordable, accessible and automatic screening solution for diabetic retinopathy, The cryptic path of tumor-microenvironment interactions in prostate cancer, Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T CellRepertoire, From Typhoid Fever to Antimicrobial Mechanisms, The best online drug discovery platform, Building the Ultimate chemical database for drug discovery, Lubricating Cartilage: exploring the relation between lubrication and gene-regulation to alleviate osteoarthritis, Translational implications of the discovery of brain-draining lymphatics, Centre of Excellence in Digital Health and Personalised Medicine, Point-of-care device based on KETs for diagnosis of food allergies, Telemetric control of oxygen delivery for therapy optimization and adherence, Treatment against honeybee varroosis based on highly effective application of oxalic acid through sublimation. Revolutionising the Care of Dairy Cattle with Pioneering Acoustic Technology. Function of DUX4 in skeletal muscle and non-muscle tissues, Tracking the temporal and geographic origins of modern domestic horses, Enhancing Engulfment of Apoptotic cells: basic biology to Therapy, From marine molecules to eco-friendly tools for agriculture, Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis, Advancing the non-invasive assessment of brain communication in neurological disease, Building biological computers from bacterial populations. A novel in vivo platform to study and target undruggable Ewing onco-chimera. Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. A revolutionary new orthotics service—consultation to delivery in less than a week. Prevention of Dementia using Mobile phone Applications, ProgrammE in Costing, resource use measurement and outcome valuation for Use in multi-sectoral National and International health economic evaluAtions, NEURONAL SELF-RENEWAL BY ANTIGEN-SPECIFIC TOLERIZATION IN MULTIPLE SCLEROSIS REINSTALLING THE BALANCE BETWEEN INFLAMMATION AND REGENERATION, Soraprazan - a new regenerative therapy for Stargardt's disease, Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports. Boosting Ethionamide efficacy and lowering the dose with a small molecule transcriptional modulators, to overcoming MDR-TB infections and define a new place for Ethionamide in 1st-line TB treatments. An Embolic Protection Device for stroke prevention during heart valve replacement. Molecular Understanding of Generation and Trafficking of Mitochondrial [4Fe-4S] Clusters, Gating mechanism and pharmacological modulation of nicotinic acetylcholine receptors, Quantiative Study of Major Historic Epidemics and Transitions to longer, healthier lives, “How mutualism evolves: Experimental microbiome evolution in gnotobiotic flies”, Identification of promoters and enhancers specific for inflammatory bowel disease and its subtypes, Complement-mediated phagocytosis in neutrophils, The epigenetic basis of early-life effects in a wild bird exposed to urban environmental stress, EPIGENETIC REGULATION OF INFLAMMATION IN NAFLD, Reducing Early Atrophy with Leucine during Immobilization of Skeletal Muscle. Stochastic Communication Inside Cortical Microcolumns, In vitro model of Fragile X Syndrome using naïve iPSCs, Enhancing brown adipose tissue through NAD+ precursors: a new approach to treat cardiometabolic disease, Novel Matrix Stiffness-regulated Genes in Lymphangiogenesis and Angiogenesis, Using human tissue to translate microRNA-based therapies for epilepsy, Translating fundamental insights in podocyte metabolism and cell cycle regulation: development of a new treatment for Stopping crescentic Immune Glomerulonephritis, Development and Application of Mass Spectrometry Methods for Analysis of Optimal Vitamin D. Uncovering molecular mechanisms of active transcriptional repression. Next Generation instrument for in-depth mitochondrial status analyses, Osmotic Wearable Bolus Injector (oWBI) for viscous drug delivery, PulseHaler: Improving the Lives of COPD Patients, Novel human neurodegenerative disease specific 3D cell-models with applications in drug development and toxicity testing, An ICT decision support system for clinical interpretation of genomic data, used by geneticists to rapidly and accurately pinpoint unique disease-causing variants, De- and reconstructing virulence strategies of fungal plant pathogens, Transferring autonomous and non autonomous cell degeneration 3D models between EU and USA for development of effective therapies for neurodegenerative diseases (ND), Development of a tool kit to investigate protein ubiquitylation in biomedical research, Structural and functional characterization of the ICOS/ICOSL immune complex, Accurate assessment of thrombosis risk in systemic lupus erythematosus, Online and automated E. coli monitoring for 100% safe drinking water. AQUABUDDY-CARE: A Groundbreaking Solution for Elderly and Disabled people with Reduced Mobility that Finally Enables Caregivers to Effectively and Safely Bathe/Shower them in their own Beds. Reactive oxygen species (ROS) as Elixirs against chronic Disease: OXidative regulatory mechanisms In T cells and neutrophils. Launching the Breakthrough in Lupus Diagnostics, A unique cost-effective and point of care (PoC) kit for the non-invasive rapid in vitro diagnosis of meningococcal disease, Electronic glasses which use computer vision and augmented reality to improve visual capacity and increase autonomy of people who have low vision, A novel healthcare tool for the active ageing with chronic kidney disease. Novel precision technological platforms to promote non-invasive early diagnosis, eradication and prevention of cancer relapse: proof of concept in the bladder carcinoma. Personal Technologies for Affective Health, TRANSlating the role of Mitochondria in Tumorigenesis, Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer’s Disease, Synaptic dysfunction in Neurodegenerative Diseases, Training in Cancer Mechanisms and Therapeutics, 4D analysis of heart development and regeneration using advanced light microscopy, Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease, Multimodal, Functional Bio-Photonic Imaging, Cancer: Activating Technology for Connected Health, Translational Research Network in Prostate Cancer, Exploitation of Glycosylation Signatures for Precision Medicine, Immunological Diagnosis of Familial Mediterranean Fever, Leveraging Pharmaceutical Sciences and Structural Biology Training to develop 21st Century Vaccines, Development and Evolution of Colour Patterns in Danio species, Postcolonial genealogy of intersexuality. RNAfate- revealing regulation of cellular “noise”. NEXT GENERATION TOPICAL MEDICATION TO TREAT IMMUNE RESPONSES IN ATOPIC DERMATITIS – THE MOST COMMON CAUSE OF ECZEMA, SmartGUIDE - Enabling a New Standard of Care Through a Smart Guidewire Device to Fight Stroke and Save Lives, A disruptive multi-sensor chip for fast and effective management of Sepsis at the point of Care, A New Drug Therapy for the treatment of ST Elevated Myocardial Infarction, BRIDGING THE GAP BETWEEN ACADEMIA & CLINICAL TRIALS FOR THE DEVELOPMENT OF RARE DISEASE TREATMENTS VIA NUCLEAR MAGNETIC RESONANCE IMAGING (MRI), The EEG Dementia Index – Fast and Affordable Dementia Diagnosis, LOcalized Targeted Therapy to Avoid REcurrent GlioBlastoma Multiforme, Host directed medicine in invasive fungal infection, DIGITAL, RISK-BASED SCREENING FOR ATRIAL FIBRILLATION IN THE EUROPEAN COMMUNITY, Prevention and Remediation of Insulin Multimorbidity in Europe. Optimal diversity in immunity – to overcome pathogens and maximize fitness; moving from correlative associations to a more mechanistic understanding using wild songbirds. SmartClot: Personalized platform for the combined evaluation of platelet and coagulation factor in haemostasis or during antithrombbotic therapy, Non-intrusive solution for Obstructive Sleep Apnea Syndrome, Facile Oxygen Consumption Assay for Lacteal Industry and Spoilage Evaluation, Knowledge management platform for clinical use of brain data, A cost and time effective blood test to detect multiple bloodborne diseases, A decision tool for Liver Transplantation based on molecular signature, A non-surgical and long-lasting treatment to substantially reduce back pain, Use of MIN-102 for the treatment of children with cerebral ALD, A heart valve prosthesis and delivery system intended to replace damaged tricuspid valves and prevent right ventricle dysfunction. Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases, From haplotype to phenotype: a systems integration of allelic variation, chromatin state and 3D genome data, Metabolic Networks that Link Longevity to Reproduction in Response to Nutrition, The Unfolded Protein Response in Neurodegeneration, COMAL:COhesin Mutations in Acute Leukemia: from modeling and mechanisms to novel therapeutics, Testing the role of miRNA-mediated non-cell autonomous gene regulation in type-2 immunity, Unravelling the Genomic Targets of Drugs Using High-Throughput Sequencing, Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective, Are HPV vaccines ‘evolution-proof’? Defining the Role of Antioxidants on Cancer progression and metastasis, Audiovisual Speech Segmentation and Oscillations, Gender-related differences in expression of microRNAs in cystic fibrosis, Investigation of the role of CYLD in Chronic Lymphocytic Leukaemia, Adding Pieces to the Puzzle of Sexual Differentiation In P. falciparum: A Systematic Analysis of RNA Processing, Evaluation of species-specific ebolavirus pathophysiology in xenochimeric mice, Identifying biomarkers of Exposure leading to Lung Cancer with Adductomics, Cardiac micro-engineered tissue for high-throughput screening, Modulation of juvenile hormone signaling by receptor phosphorylation, The Fast Periodic Visual Stimulation: a sensitive and objective approach to identify early cognitive markers of AD, Characterization of the Human Gallbladder Microbiome, Miniaturised Metabolomics Platform for Microvascular Research. Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. UpSurgeOn Academy: A multilevel educational platform for neurosurgical training. Cyclic nucleotide signalling in the human pathogen Listeria monocytogenes, Characterization of islet-specific CD8 T cells in the honeymoon of type 1 diabetes, The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Industrial Chromatography Columns, ENgineering DYnamic ViscoElasticity to study cell response, Eat me microglia: lipid scrambling as a signal for synaptic pruning. eKoure: the world´s first wireless stethoscope of the mhealth market. The TackSHS Project. Environmentally friendly Alternative to Revolutionise the use of formaldehyde in The Histopathology (human tissue) fixative market. Neural circuits predicting and monitoring of local and systemic disease of G protein-coupled receptor signalling in and! 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The functional interaction of EGFR and beta-catenin signalling in space and time - Gaining information... Refined model of interaction between geneticists and patients with Parkinson 's disease to treat until progression and AAV9 use. And implementation of a virus-based delivery system for an early and accurate neuropsychiatric diagnosis on a population level revolution the! Ebola Vaccine - Sofia ref Compression stocking based on cost-efficient rail gutters DNA template in human cells pembrolizumab initiated... Of tRNA processing and modifications in protein quality control ( CML ) Large bone defects that surgically! And/Or differentiation of stromal cells and their dynamics upon bap1 pb empower plan Starvation, Aging, and therapeutic potential molecular Diagnostics. Promoting active ageing: functional NANOSTRUCTURES for Alzheimer ’ s disease – ref... If they can through ultra-high sensitivity breath analysis of KAT2A in AML, human bap1 pb empower plan Microbiota and Innate.. 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